Use of computer for long hours can lead to discomfort and even injury. Carpal tunnel syndrome is the common cause of wrist pain.

The main causes of wrist pain are:

Position of the mouse not close to your hand
Wrist resting on sharp or hard edges
Not taking breaks
Poor typing techniques
Keeping fingers tensed on mouse or forceful hand grip
Bending your wrist while using the mouse
Using left handed mouse in right hand, or vice versa
Typing involving forceful grip or typing with the pinch of your fingers
Bending your wrist up, down, left or right

Symptoms of wrist pain:

You may feel aching, burning, numbness, or tingling in your palm, wrist, thumbs, or fingers.
The thumb muscles can become weak, making it difficult to grasp things. The pain may extend up to your elbow.
Swelling of the wrist can occur if you do repetitive typing on a keyboard and using a computer mouse.

To avoid wrist pain:

Rest your wrist. Keep it elevated.
Use wrist support while working at the desk. It prevents the wrist pain.
Take frequent breaks to stretch and walk. This reduces the muscle stress.
Shake your hands and wrists rapidly to increase comfort and reduce tension.
Adjust the keyboard in level with your forearms. This will save you from flexing your wrists when you are typing. [Egonomic Computer Keyboard]
Avoid sitting in the same posture all day.
Don’t keep the hands too far or too close from your body.
Use the chair that has long, wide and padded arm support.
Avoid unnecessary repetition of key strokes or mouse.
Do some wrist exercises to get relief. Bend the hands backwards so that your fingers point upward. Now flick the hands so that your fingers point forwards. Keep the hand and your lower arm in right angle with each other. In both cases keep your shoulders lowered and stretch your elbow joints.